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Trigeminal neuralgia as caused by Poison/"Vitamin A" toxicity

One of the most classic symptoms of Poison/"Vitamin A" toxicity is increased intracranial pressure, aka benign intracranial hypertension (BIH), aka pseudotumor cerebri, aka "too much pressure inside the skull".  It makes sense that this situation would likely cause 1) headaches of any/all types (including migraine), and 2) all sorts of other problems, as the brain and the 12 cranial nerves originate from this area.

Is it that modern medicine specifically doesn't want to admit that they know what the problem is, or is it that they are too dumb to figure it out?

Benign Intracranial Hypertension: A Diagnostic Dilemma

Benign intracranial hypertension (BIH) (also known as pseudotumor cerebri and empty sella syndrome) remains a diagnostic challenge to most physicians.

Sounds really tough for them to figure out, right?  Poor medicine, it's like there's no evidence out there of a major cause of this that EVERYONE is being exposed to!

Epidemiology and Risk Factors for Idiopathic Intracranial Hypertension

Another risk factor for intracranial hypertension is vitamin A intoxication. This phenomenon has been known for centuries by the Eskimo (Inuit) who hunt polar bears for fur and meat but avoid eating the liver for fear of the headaches and blurred vision that result from its ingestion. Polar bears have high hepatic vitamin A levels because they are at the top of the Arctic food chain, and therefore ingestion of the liver was likely inducing intracranial hypertension. Hypervitaminosis A associated with intracranial hypertension was further described by Gerber and colleagues in 1954 and is now a well-known association.42,43Other forms of vitamin A, such as isotretinoin (Accutane) for acne treatment and especially all-trans retinoic acid for the treatment of acute promyelocytic anemia have also been found to be associated with intracranial hypertension.4449Given the clear association between vitamin A intoxication and intracranial hypertension, it has been hypothesized that the pathogenesis of IIH involves abnormal vitamin A metabolism. Interestingly, recent studies have found increased levels of unbound retinol in the cerebrospinal fluid (CSF) of patients with idiopathic intracranial hypertension that did not receive vitamin A supplementation.50,51

Let's review what they said above, for those new to this game:

  1. Poison/"Vitamin A" toxicity is a known risk factor for intracranial hypertension.
  2. It can absolutely be caused by "natural" food Poison/"Vitamin A", as known for CENTURIES by the Eskimo/Inuit regarding polar bear liver.
  3. There is 1) a "CLEAR ASSOCIATION" and 2) a "WELL-KNOWN ASSOCIATION" between Poison/"Vitamin A" toxicity and intracranial hypertension.
  4. Poison/"Vitamin A" causing intracranial hypertension was first described in 1954 (65+ years ago!).
  5. 13-cis retinoic acid and all-trans retinoic acid (ATRA) are created within our bodies from carotenoid and retinoid forms of Poison/"Vitamin A" we ingest.  Both of these drugs have been associated with causing intracranial hypertension. Our bodies make these retinoic acids as part of the Poison/"Vitamin A" detox/degradation pathways.
  6. Increased unbound retinol--NOT bound to retinol-binding protein RBP, the very thing that PROTECTS US from Poison/"Vitamin A"--have been found in the cerebrospinal fluid of those with intracranial hypertension of people who HAD NOT TAKEN POISON/"VITAMIN A" SUPPLEMENTS.  Read #2, #5, and then this #6 again.  Poison/"Vitamin A" toxicity is happening from foods, pharmaceuticals, and in people who do NOT take Poison/"Vitamin A" supplements. Please stop believing the twits on the interwebz who keep repeating that this problem only happens from "synthetic" forms of Poison/"Vitamin A".  The science shows quite distinctively that they are WRONG.

So, is it really a "diagnostic dilemma", or is science and medicine simply refusing to look under the giant rock of Poison/"Vitamin A" toxicity sitting right in front of them?

On to trigeminal neuralgia.  Is it connected to increased intracranial hypertension?  Yes.  From the same "diagnostic dilemma" page quoted above:

Benign Intracranial Hypertension: A Diagnostic Dilemma

Trigeminal neuralgia and headache have been noted as in patients with elevated CSF pressure and BIH [3940].

Try going and searching through that same paper for even ONE mention of Vitamin A.  There isn't even ONE.  Again, is it a lack of competence or are they actually trying to hide something?  You decide.  It's really hard to find something that one isn't looking for, no?

Let's do a real-world case study, connecting dots that modern medicine can't even begin to fathom.

Isolated intracranial hypertension presenting with trigeminal neuropathy.

The entire article is at the link.  The title explains the connection well enough.  The part I want to cover is what CAUSED the problem in the first place, because when you learn what I have to teach here, you'll be able to see the cause(s) of modern chronic health problems everywhere, as I'm exposing and teaching about on this website:

In December 1991, a 20-year old woman presented to the casualty department with headache and numbness initially affecting the right side of the lips before spreading to involve the right side of the face. She had restarted the oral contraceptive pill two months previously after a one-year break. There was no other relevant history.

Oral contraceptive pills are birth control pills.  Birth control pills SLOW DOWN the normal breakdown of retinol Poison/"Vitamin A" and thus increases the rate and severity of Poison/"Vitamin A" toxicity in women.  Please see the link for my gigantic article on this, backed by the weight of the scientific literature.  This is simply one way that these problems are caused indirectly and seem so "hidden" to modern medicine.  This woman gave herself Poison/"Vitamin A" toxicity by taking birth control pills, which then caused her intracranial pressure to go up (known connected issue), which then caused her trigeminal neuralgia (less well-known yet connected issue).  This is just one type of connection, as there are many different paths to Poison/"Vitamin A" toxicity.

Modern medicine seems to have no good options to treat trigeminal neuralgia (and headaches of all types, including migraine) other than heavy drugs.  If you'd like to go after the cause, then I'd suggest the Poison/"Vitamin A" and Glyphosate Detox Program.

Dr. Garrett Smith, the "Nutrition Detective"
Licensed Naturopathic Physician (NMD) in Arizona
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