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You need to log in to create posts and topics. of many things necessary to make Retinol Binding PROTEIN

The liver makes Retinol Binding Protein (RBP) in an effort to protect our bodies from the ravages of Poison/"Vitamin A".  When we can't/don't make as much as we need to, the problems from Poison/"Vitamin A" greatly accelerate and increase in number.

Reversible hepatotoxicity associated with hepatic vitamin A accumulation in a protein-deficient patient

A 62-yr-old white male presented with edema, protein malnutrition, and abnormal liver function. He had ingested from 40,000–50,000 IU of vitamin A per day for 7 yr. Examination of liver tissue by light and electron microscopy revealed findings characteristic of an excessive accumulation of vitamin A. Liver tissue contained massive amounts of vitamin A (19,000 IU/g); however, both the serum concentration of vitamin A and retinol-binding protein were below normal, and serum RBP was not saturated.

WAIT, let us review the farce of conventional blood testing for Vitamin A through this case study!!!

  1. His liver, upon biopsy, was massively toxic with Poison/"Vitamin A".
  2. His "blood Vitamin A level", aka serum retinol, was BELOW NORMAL!
  3. His retinol-binding protein (RBP) was also BELOW NORMAL.
  4. His serum RBP was not fully saturated with retinol, which means that some of the RBP wasn't even carrying retinol inside of it.

Do you see why conventional medicine can't seem to find this problem?  The liver can be massively toxic while the blood tests look LOW!

On a normal diet the patient was able to mobilize hepatic vitamin A, as indicated 71 days later by a repeat biopsy of the liver, which then contained 9000 IU of vitamin A/g. During this time his nutrition improved, serum vitamin A rose, and serum RBP became transiently saturated.

Here's what happened:

  • He stopped taking all Vitamin A supplements.
  • He started eating adequate protein.

Due to these things, his liver was then able to protect itself better against the Poison/"Vitamin A" over time.

The amount of vitamin A ingested by this patient was less than that usually producing recognizable hepatotoxicity, and he had no extra hepatic manifestations of vitamin toxicity, consistent with a low serum vitamin A concentration and a low vitamin A to retinol-binding protein ratio. At presentation he was apparently unable to normally mobilize vitamin A from his liver, which may have been due to an accompanying protein deficiency.

Lesson:  You need enough protein for your liver to protect you against Poison/"Vitamin A".  The WHO sets the minimum total intake of protein per day at 50 grams.  I would suggest you hit this number and consider going even higher, whether you are a vegan, vegetarian, or anything else.  Also, remember that just because nearly all foods have protein, they don't all have the same amount/concentration.  Figure out how much you are eating and adults should try to shoot for 50 grams AT MINIMUM per day.

Dr. Garrett Smith, the "Nutrition Detective"
Licensed Naturopathic Physician (NMD) in Arizona, home of the Love Your Liver program
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