Research Forum

Forum Navigation
You need to log in to create posts and topics.

NO, Vitamin D does NOT protect one against Poison/"Vitamin A" toxicity, or vice versa.

Some people out on the Wild West of the interwebz like to make the claim that Vitamin D somehow protects a person against Poison/"Vitamin A" toxicity, and vice versa.  I found one study to support this claim (see bottom of post). However, based on my own experience, the physiological effects of both compounds (both raise calcium in the system),a direct study on rats, and a case study in the literature, the case seems clear that the OPPOSITE is true...that too much of both together will cause a synergy of PROBLEMS from too much calcium precipitating/crystallizing all throughout the body (that's what it does, that's how calcium excess causes disease).

First, let me add my experience to the matter.  A person contacted me, saying that they had poisoned themselves with Vitamin D supplements.  I said to this person that they needed to do some testing (hair mineral analysis is particularly good at assessing long-term calcium flow in the body, which is relevant to the below mechanisms) to find out where they were at, so I could best help him.  He wanted to know how much Vitamin A I thought he should take to "counteract" the Vitamin D toxicity he had given himself.  I said I don't know, and I didn't believe things worked that way (this was several years ago).  Regardless, I said we needed to "test, don't guess, then address".  He was not interested.  Fast forward a couple months later, he contacts me again.  He had tried megadosing himself with Vitamin A in an effort to counteract the Vitamin D toxicity.  He then proceeded to tell me in a nutshell, "it didn't work, and now I have toxicity symptoms of BOTH of them!"  He wanted to know what I thought he should do. Hopefully you would guess my answer at this point..."test, don't guess, then address".  I have not heard from this person since.  That is the first piece of evidence, your honor...

Next, the physiology of the matter...too much of either compound will elevate blood calcium too high (hypercalcemia, which then results in metastatic calcification, which is calcium deposits in the soft tissues of the body).  The PubMed links below go to a search that shows multiple research papers showing the following:

Both compounds cause the same problem, simply through different mechanisms.  Two sayings that might prove useful here are, "if you find yourself in a hole, STOP DIGGING" and "two wrongs don't make a right".

Then, a rat study using both Poison/"Vitamin A" and Vitamin D (aka calciferol):

Hypervitaminosis A

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258210/?page=3
"Calciferol and hypervitaminosis A.  Five more rats received the same diet with excess of Vitamin A, and with the addition of 1 mg. daily of calciferol. Fractures developed within all these animals within 11 days, and in some rats, haemorrhagic lesions round the eyes were noticed. At autopsy, no intramuscular haemorrhage was found, but the muscles of the legs had a purple colour suggestive of venous congestion."

Then, the case study:

Hypercalcemia, hypervitaminosis A and 3-epi-25-OH-D3 levels after consumption of an "over the counter" vitamin D remedy. a case report.

https://www.ncbi.nlm.nih.gov/pubmed/22426357
"Intoxication from vitamin D supplements has been rarely reported but, nowadays, it occurs more frequently. 3-epi-25-OH-D(3) is highly prevalent in adults and it is considered of biological relevance. We report a case of vitamin D toxicity with hypercalcemia, acute renal failure and hypervitaminosis A after consuming an over-the-counter vitamin D supplement. Our data suggest that the contribution of 3-epi-25-OH-D(3) is not altered during vitamin D toxicity, although the serum levels of 25-OH-D(3) and 3-epi-25-OH-D(3) may display a different rate of clearance. The patient also displayed hypervitaminosis A unrelated to diet, possibly caused by renal failure related to the hypercalcemia induced by vitamin D toxicity. Because of the increasing use of over-the-counter vitamin D supplements and the potential iatrogenic hypercalcemia related to hypervitaminosis A, the present case highlights the importance of evaluating both the use of (non-) prescribed medication and vitamin A status during vitamin D toxicity."

So, according to the case study above--in theory--excess Vitamin D via supplements can actually CAUSE Poison/"Vitamin A" toxicity, and both situations can CAUSE hypercalcemia.  Apparently when the hypervitaminosis A developed, the person didn't become magickally protected against the hypervitaminosis D?  Isn't that what these folks are saying should happen, if they are correct?  Right???  Sorry, it doesn't work that way.

Poison/"Vitamin A" is a toxin.  Vitamin D supplements are risky hormone therapy.  Both will calcify you and send you to an early grave, even faster when taken together.  My programs use neither of these, and you are welcome to read the testimonials to the effect of this approach.

Or, you can believe one 30-day study done on rats in 1964 and hope it is right in the long-term.  Not my choice, but you can do what you wish. (attached)

Uploaded files:
  • You need to login to have access to uploads.
Dr. Garrett Smith, the "Nutrition Detective"
Licensed Naturopathic Physician (NMD) in Arizona
Interested in my comprehensive Poison/"Vitamin A" Detox program? Contact Us
Want to work directly with me? I work with US and International clients! Contact my office
Enjoy seeing this work? Want to see more of it? Donations gratefully accepted! Click Here
If you order from iHerb, use my affiliate coupon code NCJ477 to get 5% Off!
If you order from Amazon, here is the Nutrition Restored Amazon Product List.
FaceBook Notes (aka my "blogging" for a long time)
My YouTube Channel
The goal is to eventually move everything to this website, as social media is without a doubt a great poison to humanity.
Medical Disclaimer