Forum Navigation
You need to log in to create posts and topics.

Heat

Photodecomposition and Phototoxicity of Natural Retinoids

Thermal and Photo Stability

Although RP [retinyl palmitate] is thermally more stable than retinol (6), both compounds are still thermally unstable. As shown in Figure 2, the experimental results from our laboratories indicated that 2% RP in an oil-in-water emulsion (cream) decomposed gradually at 4°C, with about 38% decomposed on day 7. Also, RP, as are retinoids in general, is chemically unstable and its chemical stability is highly dependent on environmental conditions such as solvent, temperature, and availability of oxygen (7). RP is easily thermally-isomerized to the 13-cis isomer. Thermal isomerization is favored in lipophilic solvents and emulsions containing high compositions of oils (7). Anhydroretinol is one of the major decomposition products of RP (8).

Dr. Garrett Smith, the "Nutrition Detective"
Licensed Naturopathic Physician (NMD) in Arizona
Interested in my comprehensive Poison/"Vitamin A" Detox program? Contact Us
Want to work directly with me? I work with US and International clients! Contact my office
Enjoy seeing this work? Want to see more of it? Donations gratefully accepted! Click Here
If you order from Swanson, use this affiliate link to get 15% Off Sitewide + Free Shipping on orders $50+
If you order from Vitacost, use this affiliate link to check out their current coupons/deals/discounts and get FREE shipping on orders $49+.
If you order from iHerb, use my affiliate coupon code NCJ477 to get 5% Off!
If you order from Amazon, here is the Nutrition Restored Amazon Product List.
FaceBook Notes (aka my "blogging" for a long time)
My YouTube Channel
The goal is to eventually move everything to this website, as social media is without a doubt a great poison to humanity.
Medical Disclaimer