Make sure to see the Poison/"Vitamin A" rules in a different thread in this forum about how Retinol Binding Protein is a surrogate/indirect marker of serum retinol (aka Poison/"Vitamin A") levels.
Retinol-binding protein 4 is elevated and is associated with free testosterone and TSH in postmenopausal women
The aim of this study was to understand the relationship of retinol-binding protein 4 (RBP4) with hormonal and biochemical parameters in pre- and postmenopausal women. We included 69 postmenopausal women and 27 regularly menstruating premenopausal women. Postmenopausal women had statistically significantly higher RBP4 levels when compared to premenopausal women. RBP4 levels were negatively associated with free testosterone and positively associated with thyroid stimulating hormone in postmenopausal women. In premenopausal women RBP4 was positively associated with body mass index. RBP4 levels were increased in postmenopausal women. Although the mechanism is not clear, these findings suggest that RBP4 has a role in the regulation of hormonal and metabolic parameters.
Translation: More RBP-4 = higher retinol = higher body mass index (fatter women, BMI is a ratio of weight to height) = lower testosterone = higher thyroid stimulating hormone (which implies lower thyroid function, TSH is higher in states of hypothyroidism)
Make sure to see the Poison/"Vitamin A" rules in a different thread in this forum about how Retinol Binding Protein is a surrogate/indirect marker of serum retinol (aka Poison/"Vitamin A") levels.
Retinol-binding protein 4 is elevated and is associated with free testosterone and TSH in postmenopausal women
The aim of this study was to understand the relationship of retinol-binding protein 4 (RBP4) with hormonal and biochemical parameters in pre- and postmenopausal women. We included 69 postmenopausal women and 27 regularly menstruating premenopausal women. Postmenopausal women had statistically significantly higher RBP4 levels when compared to premenopausal women. RBP4 levels were negatively associated with free testosterone and positively associated with thyroid stimulating hormone in postmenopausal women. In premenopausal women RBP4 was positively associated with body mass index. RBP4 levels were increased in postmenopausal women. Although the mechanism is not clear, these findings suggest that RBP4 has a role in the regulation of hormonal and metabolic parameters.
Translation: More RBP-4 = higher retinol = higher body mass index (fatter women, BMI is a ratio of weight to height) = lower testosterone = higher thyroid stimulating hormone (which implies lower thyroid function, TSH is higher in states of hypothyroidism)
