https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+815
"Increased plasma concentrations of vitamin A usually occur but do not necessarily correlate with the severity of toxicity."
from McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 3491]
Testing the retinyl esters fraction of the total serum retinol can show toxicity alone, yet no labs I have found test for this specific fraction.
https://www.hindawi.com/journals/isrn/2012/589792/
"Vitamin A toxicity is generally associated with increased levels of retinyl esters (the storage form of the vitamin) circulating with plasma lipoproteins unbound to retinol-binding protein (RBP). Retinyl esters react more randomly with cell membranes than the physiologically sequestered RBP and hence are a major form of vitamin A toxicity. Fasting retinyl ester concentrations >10% of total circulating vitamin A (retinol plus esters) are considered a biomarker for toxicity [146, 147]."
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+815
Laboratory findings include elevated liver enzymes and bilirubin, increased INR, hypercalcemia, elevated erythrocyte sedimentation rate and periosteal calcification on radiographs. Increased opening pressure may be noted on lumbar puncture.
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+815
"Increased plasma concentrations of vitamin A usually occur but do not necessarily correlate with the severity of toxicity."
from McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 3491]
Testing the retinyl esters fraction of the total serum retinol can show toxicity alone, yet no labs I have found test for this specific fraction.
https://www.hindawi.com/journals/isrn/2012/589792/
"Vitamin A toxicity is generally associated with increased levels of retinyl esters (the storage form of the vitamin) circulating with plasma lipoproteins unbound to retinol-binding protein (RBP). Retinyl esters react more randomly with cell membranes than the physiologically sequestered RBP and hence are a major form of vitamin A toxicity. Fasting retinyl ester concentrations >10% of total circulating vitamin A (retinol plus esters) are considered a biomarker for toxicity [146, 147]."
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+815
Laboratory findings include elevated liver enzymes and bilirubin, increased INR, hypercalcemia, elevated erythrocyte sedimentation rate and periosteal calcification on radiographs. Increased opening pressure may be noted on lumbar puncture.
